Genetic Research on Obesity

A Medical Clinic is an institution or office which provides health care services for specific medical conditions. The treatment process will be determined by the subcohort of patients and their families, depending on their specific condition. There are various reasons as to why a Medical Clinic might be located in a certain area of town. These reasons are:

For Cohort A: This group is comprised of people who are genetically predisposed to certain diseases and are thus provided with special medical attention. For example, people who have parents who were diagnosed with cancer at an early age, or those with parents who suffered from heart disease at an early age are likely to get these diseases. As such, individuals who belong to Cohort A may be more likely to develop heart disease later on in their life. As such, the aim of a Medical Clinic is to screen individuals who belong to Cohort A and thus, prevent them from developing these diseases. In this manner, the Medical Clinic aims to prevent outpatients from getting diseases like cardiovascular disease or cancer at an early age.

For Cohort B: This group consists of individuals who, though they belong to the same group but have not been diagnosed with a disease yet, might still be exposed to medical risks because of their family history. The members of this group might develop such diseases as spina bifida, or else they might develop lung disease due to genetics. For example, if both the plaintiff and the defendant (the subject of the suit) developed spina bifida in the same household, then both of the plaintiff and the defendant may be exposed to an increased risk of contracting spina bifida because of the domicile of the plaintiff. Theseauctions, via sites such as rehab are also available online.

For Phenotypic Disease: Individuals who belong to Cohort A are diagnosed with a disease when they attain the age of sixty-five or over; otherwise, individuals diagnosed with phenotypic disorder are those who have reached the age of eighteen or less. The members of Cohort A are advised to avoid excessive alcohol consumption because excessive alcohol use can increase the risks of developing phenotypic disorder, which includes the condition of familial hypercholesterolemia. On the other hand, the members of Cohort B are advised to stay away from alcoholic beverages because excessive alcohol use can increase the risks of developing coronary artery disease. However, there are still many cases where individuals from Cohort A are diagnosed with conditions even when they are under the age of sixty-five because the symptoms of these diseases are often confused with other age-related conditions.

The most common condition for subjects examined under the terms of Cohort A is obesity. There are different reasons why individuals develop obesity. Some develop obesity because they have developed increased body fat; some because they have developed increased body cholesterol levels; and some because they have developed insulin resistance (reflux syndrome) or fatty liver disease (fatty liver). In order to establish the extent of the risk of obesity among Cohort A subjects, all subjects in the study should be categorized into two groups based on their BMI. Those with higher BMI than the median value for their age (BMI) are considered to be at high risk of obesity and all such subjects should be instructed to modify their diet and lifestyle to reduce their risk of becoming obese.

The third category of subjects included in Cohort B is those who are diagnosed with familial hypercholesterolemia but their relatives are not. This condition is also referred to as familial Mediterranean hypercholesterolemia. Patients in Cohort B are diagnosed with this condition if their parents, or one of their parents, have a high level of blood cholesterol (LDL) and/or increased blood triglycerides (LDL) but their family is not predisposed to cardiovascular disease or to increased LDL cholesterol. If these subjects in Cohort A develop familial Mediterranean hypercholesterolemia, the risk of obesity increases by approximately fourfold and the chances of developing coronary artery disease (CAD) increases by approximately fourfold in subjects within this group.

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